Cell Metabolism AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration
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چکیده
Manuscript Number: CELL-METABOLISM-D-13-00308R2 Full Title: AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration Article Type: Research Article
منابع مشابه
AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration.
Macrophages control the resolution of inflammation through the transition from a proinflammatory (M1) to an anti-inflammatory (M2) phenotype. Here, we present evidence for a role of AMPKα1, a master regulator of energy homeostasis, in macrophage skewing that occurs during skeletal muscle regeneration. Muscle regeneration was impaired in AMPKα1(-/-) mice. In vivo loss-of-function (LysM-Cre;AMPKα...
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